Having protected the world from a zombie plague in PATIENT ZERO, Joe Ledger and his crack Department of Special Sciences combat team are thrown into an even more frightening crisis. A genetic-engineering program has been used to create the ultimate fighting machine - soldiers bred for war, soldiers with greater strength, higher reaction speeds and an utter disregard for pain. Theirs and others. It's a nightmare from the pages of Doctor Moreau and soon Joe and his team are up against both the big business concerns who have billions invested in the project and, on the street, adversaries bred expressly to kill them. It's enough to make you wish you were facing zombies again ...